The structure of an LIM-only protein 4 (LMO4) and Deformed epidermal autoregulatory factor-1 (DEAF1) complex reveals a common mode of binding to LMO4.
LIM-domain only protein 4 (LMO4) is a widely expressed protein with important roles in embryonic development and breast cancer.It has been reported to bind many partners, including the transcription factor helo baby salve Deformed epidermal autoregulatory factor-1 (DEAF1), with which LMO4 shares many biological parallels.We used yeast two-hybrid as